Tag: hydrophobic scores of neighbors (HSN)
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Proteolytic Characteristics of Cathepsin D Related to the Recognition and Cleavage of Its Target Proteins
Cathepsin D (CD) plays an important role in both biological and pathological processes, although the cleavage characteristics and substrate selection of CD have yet to be fully explored. We employed liquid chromatography-tandem mass spectrometry (LC-MS/MS) to identify the CD cleavage sites in bovine serum albumin (BSA). We found that the hydrophobic residues at P1 were […]