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April 20, 2024
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Synthesis of tertiary alkylphosphonate oligonucleotides through light-driven radical-polar crossover reactions
5 min read
Nucleic Acids
Synthesis of tertiary alkylphosphonate oligonucleotides through light-driven radical-polar crossover reactions
December 13, 2023
Site-specific replacement of phosphorothioate with alkyl phosphonate linkages enhances the therapeutic profile of gapmer ASOs by modulating interactions with cellular proteins
5 min read
Nucleic Acids
Site-specific replacement of phosphorothioate with alkyl phosphonate linkages enhances the therapeutic profile of gapmer ASOs by modulating interactions with cellular proteins
December 6, 2023
Cell-Penetrating Peptides in Diagnosis and Treatment of Human Diseases: From Preclinical Research to Clinical Application
8 min read
Peptides
Cell-Penetrating Peptides in Diagnosis and Treatment of Human Diseases: From Preclinical Research to Clinical Application
December 5, 2023
Synthetic Life with Alternative Nucleic Acids as Genetic Materials
5 min read
Nucleic Acids
Synthetic Life with Alternative Nucleic Acids as Genetic Materials
December 3, 2023