Tag: photolabile protecting groups

Highly Efficient Photolabile Protecting Groups with Intramolecular Energy Transfer

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Goris The light sensitivity of photolabile protecting groups of the nitrophenylpropoxycarbonyl (NPPOC) type was enhanced by up to a factor of 25. This was achieved by covalently linking the protecting group to a sensitizer with a much better absorptivity and the ability to transfer its electronic excitation to the protecting group (see scheme).