Product Name: Tyrosol-NW(Carbamate)
IUPAC Name: ((4-hydroxyphenethoxy)carbonyl)-L-asparaginyl-L-tryptophan,
Description: Tyrosol, 2-(4-Hydroxyphenyl) ethanol, is a phenolic compound abundantly found in olive oil, white wine and plant extracts. Tyrosol has numerous biological activities, including antioxidant and neuro- and cardio-protective effects, and exhibits anti-inflammatory properties. Tyrosol treatment inhibited TNF-α, IL-1β and IL-6 production by LPS-stimulated human peripheral blood mononuclear cells and decreased PGE2 and NO levels produced by phorbol ester-stimulated RAW264.7 macrophages. Asn-Trp (NW), derived from computer-aided simulation of dioscorin hydrolysis, exhibits antioxidant and antiglycation activities, which thus shows the benefits of the yam tuber as an antioxidant-rich food.NW and QW (50–200 μM) showed protection against methylglyoxal-induced cell deaths in human umbilical vein endothelial cells. The antioxidant assays included hydroxyl radical-scavenging activity, anti-AAPH-induced hemolysis, and ORAC activity. NW had a significantly higher antioxidant activity than had QW and performed much better than carnosine, homocarnosine, or GSH.