Description

Product Name: Stearyl-transportan10

Synonyms: Stearyl-TP10, PF3, Stearyl-Ala-Gly-Tyr-Leu-Leu-Gly-Lys-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2,

Cat#: 3221001

M.F.: C122H219N27O24

M.W.: 2448.26

Description: PepFect3 (PF3) is the closest TP10 analog with only an additional stearyl moiety at the N-terminus, allowing the formation of stable peptide/oligonucleotide complexes.Transportan10 (TP10) is one of the well-known CPPs, a truncated analog of transportan with the N-terminal fragment from the galanin neuropeptide and the C-terminal fragment from the wasp venom peptide mastoparan and an extra lysine positioned between the two fused sequences. It belongs to a group of the hydrophobic CPPs with strong affinity to a model membrane already at low concentrations. TP10 showed not only high transduction efficiency but also high cell toxicity.