Product Name: Phosphorylcholine-Geranylgeraniol
Synonyms: Phosphorylcholine-Tetraprenol, Phosphorylcholine-Trans-Geranylgeraniol,
IUPAC Name: (2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl (2-(trimethylammonio)ethyl) phosphate,
Description: Phosphorylcholine (PC) proved to be the immunomodulatory molecule. Immune regulation functions of some helminthes are attributed to the phosphorylcholine (PC) moiety. Farnesol (FOH) and geranylgeraniol (GGOH) are produced by dephosphorylation of farnesyl pyrophosphate and geranylgeranyl pyrophosphate, respectively, although they are in turn phosphorylated to their pyrophosphates. The two isoprenoids are increasingly known to display multiple functions. GGOH was shown to be a ligand for peroxisome proliferator-activated receptors α and γ and a negative regulator of liver X receptor α, and its constant synthesis in mouse brain was suggested to be essential for learning. Geranylgeraniol has antibacterial activity against S. aureus FDA209P and that its mode of action involves damage to cell membranes, being similar to that of farnesol.