Description

Product Name: PepFect 14

Synonyms: PF14, Stearyl-Ala-Gly-Tyr-Leu-Leu-Gly-Lys-Leu-Leu-Orn-Orn-Leu-Ala-Ala-Ala-Ala-Leu-Orn-Orn-Leu-Leu-NH2,

Cat#: 3221002

M.F.: C120H217N27O23

M.W.: 2406.22

Description: PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation. PepFect 14 (PF14) is a modified version of our previously reported peptide, stearyl-transportan10 (stearyl-TP10), where we utilized ornithines and leucines instead of lysines and isoleucines. PepFect 14 (PF14), forms non-covalent nanocomplexes with short interfering RNA (siRNA), which are able to elicit efficient RNA-interference (RNAi) response in different cell-lines. RNAi effect is obtained at low siRNA doses with a unique kinetic profile.