Product Name: OSA-Geraniol
IUPAC Name: (E)-2-(2-(((E)-3,7-dimethylocta-2,6-dien-1-yl)oxy)-2-oxoethyl)dec-3-enoic acid,
Description: Geraniol is a natural monoterpene classified in the GRAS category. Geraniol (3,7-dimethylocta-trans-2,6-dien-1-ol) is an acyclic monoterpene with a water solubility of 100 mg/L at 25°C and an n-octanol/water partition coefficient of 2.65. It is abundant in essential oils extracted from lemongrass, rose, lavender and other aromatic plants. It is known to exert a wide spectrum of pharmacological activities, namely antimicrobial, anti-inflammatory, antioxidant and neuroprotective effects. For example, oral administration of geraniol as an antimicrobial agent effectively prevented colitis-associated dysbiosis and decreased the systemic inflammatory profile of colitic mice. Moreover, oral administration of geraniol supported the ability of dopaminergic neurons to survive free radical injury by inducing the production of antioxidant enzymes and reducing the expression of apoptotic markers. These properties indicate that geraniol is a natural compound potentially able to prevent the progression of Parkinson’s disease and other neurodegenerative disorders and to serve as a therapeutic agent in the treatment of a wide range of cancers, including lung, pancreatic, hepatic and kidney tumors. Thermal stability improvement was achieved by OSA modification.