Product Name: Hydroxytyrosol-Xentry
Synonyms: Hydroxytyrosol-LCLRPVG, Hydroxytyrosol-Leu-Cys-Leu-Arg-Pro-Val-Gly,
IUPAC Name: ((3,4-dihydroxyphenethoxy)carbonyl)-L-leucyl-L-cysteinyl-L-leucyl-L-arginyl-L-prolyl-L-valylglycine,
Description: 3,4-Dihydroxyphenylethanol (hydroxytyrosol, DOPET), a major phenolic compound in olive oil and red wine, has powerful antioxidant properties and presents several interesting aspects for human health. For example, results in vitro demonstrated that hydroxytyrosol inhibits human low-density lipoprotein oxidation, scavenges free radicals, inhibits platelet aggregation and leucotriene production for human neutrophils, and confers cell protection. It has also been demonstrated that hydroxytyrosol acts in vitro as an antibacterial agent against both gram-positive and gram-negative bacteria. Xentry(LCLRPVG) was initially isolated from the 154 amino acid residue X-protein, which is just one of six proteins encoded by the hepatitis B virus that chronically infects 400 million people worldwide. Xentry represents a unique class of CPP in that it is very short, has only a single charged arginine residue, bears no resemblance to any previously described CPP, and does not share with other CPPs the ability to enter cells by a non-endocytic route.