Product name: Hyaluronic acid-Phe-Phe-Oet
Molecular Weight: 1000-1500Kdal
Peptide Content: 1.0%-10.0%
Format: White to slight yellow solid
Description: Hyaluronic acid (HA), also named hyaluronan, is a high molecular weight (105–107 Da) naturally occurring biodegradable polymer. HA is an unbranched non-sulfated glycosaminoglycan (GAG) composed of repeating disaccharides (β-1,4-D-glucuronic acid (known as uronic acid) and β-1,3-N-acetyl-D-glucosamide). Hyaluronic acid is one of the major elements in the extracellular matrix (ECM) of vertebrate tissues. It is available in almost all body fluids and tissues, such as the synovial fluid, the vitreous humor of the eye, and hyaline cartilage. This biopolymer functions as a scaffold, binding other matrix molecules including aggrecan. It is also involved in several important biological functions, such as regulation of cell adhesion and cell motility, manipulation of cell differentiation and proliferation, and providing mechanical properties to tissues. One of the most studied short building blocks is the diphenylalanine peptide (L-Phe-L-Phe; FF), the core recognition motif of the Alzheimer’s β-amyloid peptide. A series of studies have shown that the peptide and its derivatives can self-assemble into highly ordered structures and other forms with nanoscale order, such as hydrogels. A unique property of the FF building block is its ability to form hollow tubular assemblies, most likely by the closure of two-dimensional surfaces.