Product Name: Glycyrrhetinic acid-VPY
Synonyms: Glycyrrhetinic acid-Val-Pro-Tyr,
IUPAC Name: ((2S,4aS,6aS,6bR,10S,12aS,12bR,14bS)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carbonyl)-L-valyl-L-prolyl-L-tyrosine,
Description: Tripeptide VPY is a novel PepT1 substrate that can inhibit the production of pro-inflammatory mediators in vitro in intestinal epithelial and immune cells. Glycyrrhizic (GZA) and glycyrrhetinic acid (GTA), as well as their derivatives, exhibit a various biological effect, including anti-inflammatory and anti-ulcer activity. Consequently, they serve as pronounced starting materials for effective anti-inflammatory, anti-allergic and antiulcer preparations.