Product Name: Glycyrrhetinic acid-Spermidine
IUPAC Name: (2S,4aS,6aS,6bR,10S,12aS,12bR,14bS)-N-(3-((4-aminobutyl)amino)propyl)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxamide,
Description: Glycyrrhetinic acid is a major component in licorice extract. Previous studies have shown that glycyrrhetinic acid has many properties, including anti-inflammatory, anti-allergic, anti-peptic ulcer, and anti-viral activities. Its anti-inflammatory effect is particularly well known and has been applied to clinical therapy. In the polyamine biosynthetic pathway, spermidine is a precursor of spermine and is a known promoter of longevity. Spermidine has also been shown to prevent sporadic prion formation in yeast prion models. Both enhancing longevity and protection against de novo formation of yeast prions by spermidine are shown to be autophagy dependent.