Product Name: EGCG-Spermidine
Synonyms: (-)-Epigallocatechin gallate-Spermidine,
Description: Epigallocatechin-3-gallate(EGCG) inhibits 5α-reductase and represses the expression of androgen receptor genes , and thereby exhibits a potential action for the prevention or treatment of androgen-dependent disorders. Kwon et al. reported that EGCG stimulates human hair growth via proliferative and anti-apoptotic effects on dermal papilla cells. Similarly, topical EGCG was reported to reduce testosterone-induced apoptosis of hair follicles in a mouse model. Spermidine is polyamine found in citrus fruit and soybean, which has recently been shown to increase the lifespan of yeast, nematodes, and flies in an autophagy-dependent fashion. The biologically active amines, spermine, and agmatine, have specific functions on mitochondria which distinguish them from other amines.