Product Name: EDTA-Tetrasine
Synonyms: EDTA-Tetra carnosine,
IUPAC Name: (2S,21S)-2,21-bis((1H-imidazol-4-yl)methyl)-10,13-bis(2-((3-(((S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl)amino)-3-oxopropyl)amino)-2-oxoethyl)-4,8,15,19-tetraoxo-3,7,10,13,16,20-hexaazadocosanedioic acid
Description: Carnosine (β-Alanyl-L-histidine) is a naturally occurring dipeptide with numerous potential physiological functions and is formed by combining its constituent amino acids, L-histidine and beta-alanine, with the assistance of the enzyme carnosine synthetase. Carnosine is predominantly stored within skeletal muscle, and can vary widely between species. By virtue of a pKa of 6.83 and high concentrations in muscle, carnosine has been shown to be more effective at sequestering protons than either bicarbonate (pKa 6.3) or inorganic phosphate (pKa 7.2), the other two major physio-chemical buffers, over the physiological pH range. The potential physiological roles of carnosine extend beyond its function as a proton buffer. Previous research has suggested that reactive oxygen species (ROS), which are produced at an elevated rate during exercise, may contribute to muscle fatigue and exercise-induced muscle damage under certain circumstances. Carnosine has been shown to act as an antioxidant by scavenging free radicals and singlet oxygen, thereby reducing oxidative stress. Carnosine can further reduce oxidative stress by chelating transition metals, such as copper and iron.