Product name: DNBLK1
Catalog #: 3904075
CAS No.: N/A
Molecular Formula: C130H229N57O42S
Molecular Weight: 3294.68
Description: African swine fever (ASF) is also a viral disease that lacks e ective vaccines for prevention and control in the pig breeding industry; it has spread quickly as an epidemic viral disease in China since mid-2018. As a highly infectious viral disease of pigs,ASF causes fatal hemorrhagic fever after infection, resulting in a high mortality rate of nearly 100%. ASF is caused by African swine fever virus (ASFV), which is a large, enveloped, double-stranded DNA virus with icosahedral morphology and the only member of Asfarviridae family. DNBLK1 is a synthesized short peptide that consists of 28 amino acid residues and contains DLC8 binding domain; by binding to DLC8 to prevent the interaction between ASFV protein p54 and DLC8 in vitro, it may be a useful tool to retard viral replication or spread. Bruno et al. indicated that DNBLK1 can reduce the infectivity, replication, and production of ASFV, and the inhibition occurs at the early stage of the ASFV infection cycle.
Usage: For Scientific Research Use Only, Not for Human Use.
Antibiotics. 2020, 9, 801.