Product Name: Caffeic acid-Tyrosol
IUPAC Name: 4-hydroxyphenethyl (E)-3-(3,4-dihydroxyphenyl)acrylate,
Description: Caffeic acid (CA) is a decomposition product of chlorogenic acid that has the same physiological activity as chlorogenic acid does. Although CA has been reported to protect against dyslipidemia and blood glucose elevation owing to its antioxidant activity, its application is limited by poor water solubility and oral absorption. Tyrosol, 2-(4-Hydroxyphenyl) ethanol, is a phenolic compound abundantly found in olive oil, white wine and plant extracts. Tyrosol has numerous biological activities, including antioxidant and neuro- and cardio-protective effects, and exhibits anti-inflammatory properties. Tyrosol treatment inhibited TNF-α, IL-1β and IL-6 production by LPS-stimulated human peripheral blood mononuclear cells and decreased PGE2 and NO levels produced by phorbol ester-stimulated RAW264.7 macrophages.