Azelaic acid-Glycine


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SKU: 3110001 Category: Tag:


down-the-line Product Name: Azelaic acid-Glycine

adventurously IUPAC Name: 2,2′-(nonanedioylbis(azanediyl))diacetic acid,

Cat#: 3110001

M.F.: C13H22N2O6

M.W.: 302.33

Description: In 2003, Azelaic acid was first approved for clinical use as a 15% gel in the treatment of rosacea. Topical azelaic acid has been demonstrated as safe in pregnancy and is thus classified as a category B drug; the agent also appears safe for use during lactation. azelaic acid is a reversible inhibitor of tyrosinase and other oxidoreductases in vitro and that it inhibits mitochondrial respiration. It can also inhibit anaerobic glycolysis. Both in vitro and in vivo it has an antimicrobial effect on both aerobic and anaerobic (Propionibacterium acnes While the exact mechanism(s) of antimicrobial activity remains to be fully elucidated, azelaic acid has effects on metabolism, enzymatic activity, and intracellular pH.

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