Product Name: Asiatic acid-RER
Synonyms: Asiatic acid-Arg-Glu-Arg,
Description: Asiatic acid (AA)is a pentacyclic triterpenoid derived from the tropical medicinal plant Centella asiatica (family-Apiaceae). Beneficial effects of AsA have been reported in wound healing, UV-induced photoaging, glutamate- or β-amyloid-induced neurotoxicity and hepatofibrosis. Furthermore, there are numerous reports suggesting the strong neuroprotective and anti-cancer efficacy of AsA. For example, AsA treatment has been reported to induce apoptotic death in human hepatoma and malignant glioma cells through enhancing the intracellular calcium release. Amino acid sequences containing the palindromic tripeptide RER, matching amino acids 328-330 of the amyloid precursor protein APP,RER and its derivatives may offer a novel approach to enhancing the neuroprotective effects of APP and alleviating the effects of memory loss in the early stages of Alzheimer’s disease.