Adenine dinucleotides (Ap4A)

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San Miguel De Abona Quantity: 1Gram

SKU: 9105003 Category: Tag:


Shādegān Product name: Adenine dinucleotides (Ap4A) Synonym: Adenine dinucleotide 5’-5’-tetraphosphate, P1,P4-diadenosine-5′-tetraphosphate,

Catalog #: 9105003

Purity: 90%

CAS No.: N/A

Molecular Formula: C20H24N10Na4O19P4

Molecular Weight: 924.32

Description: Adenine dinucleotides (Ap3A, Ap4A, Ap5A, Ap6A) are stored in secretory granules of thrombocytes, chromaffin cells and neuronal cells. After release into the extracellular space, the dinucleotides exhibit divergent biological effects on a variety of target cells and organs. The dinucleotides are metabolized by soluble enzymes in the blood plasma as well as by membrane-bound ectoenzymes of endothelial cells, smooth muscle cells, and other cell types. The adenosine polyphosphates have autocrine function for thrombocytes. Ap3A at low concentration reversibly activates isolated platelets. The mechanism of activation has been elucidated by showing a continuous cleavage of Ap3A, leading to the formation of ADP which is a known agonist of the P2T receptor on thrombocytes. Ap4A and other dinucleotides act as antagonists and inhibit platelet activation.


Usage: For Scientific Research Use Only, Not for Human Use.

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