One-pot conversion of alkyl aldehydes into substituted propanoic acids via Knoevenagel condensation with Meldrum’s acid

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Reaction of a range of alkyl aldehydes and Meldrum’s acid in triethylammonium formate (TEAF) at 100 °C generates substituted propanoic acids in a single step. (Tetrahedron Letters.,Volume 51, Issue 38, 22 September 2010, Pages 4972-4974.)

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